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  6. Dual Z-scheme In2s3/bi2s3/zns Heterojunction With Broad-spectrum Response As A Photoactive Material For Ultrasensitive Detection Of Environmental Pollutant Tetracycline

Dual Z-scheme In2S3/Bi2S3/ZnS heterojunction with broad-spectrum response as a photoactive material for ultrasensitive detection of environmental Pollutant tetracycline

Li Chen1, Yu-Shuang Jin1, Jun-Ying Qin2

  • 1Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, Chongqing Engineering Laboratory of Nanomaterials & Sensor Technologies, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, PR China.

Biosensors & Bioelectronics|June 14, 2025

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View abstract on PubMed

Summary

A novel dual Z-scheme heterojunction biosensor was developed for ultrasensitive detection of tetracycline (TC) in environmental samples. This advanced photoelectrochemical (PEC) biosensor offers a highly sensitive method for monitoring antibiotic pollution.

Area of Science:

  • Materials Science
  • Analytical Chemistry
  • Environmental Science

Background:

  • Environmental pollution by antibiotics like tetracycline (TC) poses a significant threat.
  • Existing photoelectrochemical (PEC) biosensors often suffer from low sensitivity and background noise.
  • Developing highly sensitive and reliable methods for TC detection is crucial for environmental monitoring and food safety.

Purpose of the Study:

  • To develop a novel dual Z-scheme heterojunction In2S3/Bi2S3/ZnS (IBZS) with a core-shell structure for enhanced PEC performance.
  • To establish a highly sensitive PEC biosensor for the ultrasensitive detection of tetracycline (TC).
  • To mitigate the DNA duplex breathing effect and suppress background noise for improved detection accuracy.

Main Methods:

  • Fabrication of a dual Z-scheme heterojunction IBZS material with a core-shell structure.
  • Construction of a PEC biosensor utilizing the IBZS material.
  • Implementation of a target-triggered entropy-driven DNA reaction (TEDR) strategy to enhance signal-to-noise ratio.
  • Optimization of the PEC detection parameters for TC analysis.

Main Results:

  • The dual Z-scheme heterojunction IBZS exhibited a strong PEC response due to broad-spectrum absorption and efficient carrier migration.
  • The redesigned TEDR effectively suppressed nonspecific background noise, significantly enhancing detection sensitivity.
  • The developed PEC biosensor achieved ultrasensitive detection of TC in the range of 1.0 fM to 10 nM.
  • An exceptionally low detection limit of 0.54 fM for TC was achieved, surpassing current methods.

Conclusions:

  • The novel dual Z-scheme heterojunction IBZS material and TEDR strategy provide a high-performance PEC biosensor for ultrasensitive TC detection.
  • This approach offers a promising new avenue for designing advanced PEC photoactive materials for environmental pollution monitoring.
  • The developed biosensor is expected to be valuable for analyzing antibiotics in environmental samples and ensuring food quality control.
Keywords:
Antibiotic detectionDual Z-scheme heterojunctionEntropy-driven DNA reactionPhotoelectrochemical

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